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Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune rheumatic diseases, which are characterised by chronic inflammation of the skeletal muscle. Diagnosis of myopathies is challenging due to the rarity of the diseases and the possibility of overlap syndromes. Serological diagnostics therefore play a key role, as autoantibodies are important biomarkers for the differentiation of clinically indistinguishable IIM subforms.
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EUROIMMUN offers a comprehensive range of tests for the detection of myositis-relevant autoantibodies. The EUROLINE profiles for myositis diagnostics are the most comprehensive commercially available line blots and allow monospecific detection of up to twenty autoantibodies in one incubation, including – the worldwide exclusive – cN-1A for differential diagnostics of inclusion body myositis, a rare form of IIM.
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Autoantibodies in myositis: An upgrade for comprehensive serological testing
The autoimmunogenic myositides (idiopathic inflammatory myopathies, IIM) constitute a group of systemic autoimmune rheumatic diseases that are characterized by chronic inflammation of muscles. Unfortunately, the general misdiagnosis rate is high resulting in a delay to diagnosis of several years. Moreover, a significant proportion of patients with IIM suffer from a generalized feeling of severe illness due to the damage caused by both the disease and its treatment. Autoantibodies are useful biomarkers to differentiate clinically indistinguishable subforms of IIM. Despite the low prevalences and isolated occurrence of many autoantibodies in IIM, they constitute the basis for serological diagnostics. The diagnostic informa- tion is maximized by employing comprehensive multiparametric assays covering both myositis-specific and myositis-associated autoantibodies.
Licda.Rosa Hernandez & Lic. Oscar Sandoval
INSULAB S.A. de C.V
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Clinica Corazon de Maria, Colonia Escalon
Jose Ricardo Acosta
DIPRODI (Distribuidora de Productos Para DiagnosticoS. De R.L. de C.V.)
ph 22307121 Tegucigalpa
Residencial Palza, Bloque 32, Casa No. 1
Ms. Triana Delfin
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Phone: +598 2 916 8969
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Mr Stephen Harland-Smith
ESL Biosciences (Australia) (2012) Pty
2150 New South Wales
2-4 Giffnock Avenue
PO Box 202 / Macquarie Park Business Hub /North Ryde BC, NSW 1670, Australia Suite 3
Dr. Khalifa Eltayeb Khalafalla
K-BIOanalytica Co. Ltd.
Al -Sayed Abdel Rahman Street / Al Qasr street Junction
Rayan Specialized laboratory Building/ P.O.Box 11656
Khalid Abdalla Abdelrahim AL Fahim
AL Fahim Health Care Solutions LLC
Boulevard Plaza Tower 2, Office 1904
United Arab Emirates