Tick-borne diseases: a severe health threat

Along with Lyme borreliosis, tick-borne encephalitis is the most common tick-borne disease in Europe.

Borreliosis is caused by bacteria transmitted to humans through the tick bite. The disease is most frequent in Europe but also occurs in North America and Asia.2 There is no vaccine against borreliosis but most infections can be treated effectively with antibiotics.2 

Tick-borne encephalitis (TBE) is a viral infection of the central nervous system which, in the majority of cases, also results from the bite of an infected tick.3 Every year, about 10,000-12,000 cases are reported but actual numbers are assumed to be much higher.3 In contrast to borreliosis, an effective vaccination is available against TBE.

Although Crimean-Congo haemorrhagic fever (CCHF) is rare in Europe, cases have been reported in in the Balkan and Mediterranean regions.4 CCHF is a life-threatening tick-borne disease caused by a virus that can also spread from human to human via contaminated blood. According to the World Health Organization (WHO), CCHF is currently one of the most important infectious diseases with pandemic potential and is therefore included in the WHO priorities for research and product development.5

Furthermore, climate change is contributing to the spread of tick-borne diseases by permitting expansion of tick habitats due to warming average temperatures. This increases the risk of such diseases in previously less affected areas.6

1 ECDC: Key messages about tick-borne encephalitis and tick-borne diseases – as of January 2025
2 ECDC: Factsheet about Borreliosis – as of January 2025 (last update: March 2016)
3 WHO: Tick-borne encephalitis – as of February 2025
4 ECDC: Crimean-Congo haemorrhagic fever – as of March 2025
5 ECDC: Factsheet for health professionals about Crimean-Congo haemorrhagic fever – as of March 2025 (last update: December 2023)
6 CDC: Vector-Borne Diseases – as of March 2025 (last update: March 2024)


Infection diagnostics with EUROIMMUN

Early detection and treatment of tick-borne diseases may be crucial to prevent severe complications – e.g. for Borrelia infections.2 For diseases for which no vaccine is available, e.g. CCHF, management of infection outbreaks relies on rapid identification of cases and appropriate control measures.5

EUROIMMUN offers a broad range of high-quality test systems for reliable diagnostics of tick-borne diseases. The portfolio focuses on serological assays for the detection of antibodies against Borrelia, TBE and CCHF virus. Since Borrelia and TBE virus can cause neurological diseases, the determination of intrathecally produced antibodies in cerebrospinal fluid (CSF) is also possible with some of our test systems.

Other relevant parameters:

Bordetella        Measles virus

Thinking globally – acting locally
With over 35 years of experience in the field of laboratory diagnostics, we develop and globally distribute complete diagnostic solutions that are tailored to your local needs. Working together with local health and scientific authorities we stay aware of novel and/or urgent infection events and deliver appropriate solutions for infectious diseases diagnostics all over the world. With our unrivalled in-house development and production of diagnostic test systems as well as our automation and software solutions, we are able to respond rapidly to both small and large infection outbreaks, providing support to national and international health entities when and where it is needed.
Thinking globally – acting locally


Broad portfolio for reliable diagnostics of tick-borne diseases

Assays for screening and confirmation, also in CSF

Borrelia

  • PCR

    • GeneProof Borrelia PCR Kit 
      (manufactured by GeneProof)
      Order no. MH 0037

    Icon Real-Time PCR
  • ELISA


    Icon ELISA
  • Immunoblot

    • Anti-Borrelia EUROLINE-RN-AT (IgG) DN 2131 G
    • Anti-Borrelia EUROLINE-RN-AT (IgM) DN 2131 M
    • Anti-Borrelia EUROLINE EN-AT-adv (IgM) DN 2131-2 M
    • Anti-Borrelia EUROLINE-WB (IgG, IgM) DY 2131-1 G / M
      → Data sheet (PDF)

    Icon Immunoblot
  • EUROMicroblot

    • EUROMicroBlot Anti-Borrelia (IgG) KN 2131-9601 G
    • EUROMicroBlot Anti-Borrelia (IgM) KN 2131-9601 M

    Icon EUROMicroblot
  • ChLIA


    Icon ChLIA
  • Indirect immunofluorescence assays

    EUROPLUS: Anti-Borrelia afzelli and burgdorferi IIFT plus VlsE and OspC (IgG, IgM) FI 2136-1 G / M
    → Data sheet (PDF)


    IFA

Tick-borne encephalitis virus

  • ELISA

    • Anti-TBE Virus ELISA 2.0 (IgG) EI 2661-9601-2 G
      → Data sheet (PDF)
    • Anti-TBE Virus ELISA 2.0 (IgM) EI 2661-9601-2 M
      → Data sheet (PDF)
    • CSF: Anti-TBE Virus CSF ELISA 2.0 (IgG) EI 2661-9601-2L G
    • CSF: Anti-TBE Virus ELISA (IgM) EI 2661-9601-L M

    Icon ELISA
  • Indirect immunofluorescence assays

    • Anti-TBE virus IIFT FI 2661 A / G / M
    • Flavivirus Profile 2 FI 2661-2 G / M

      Different formats available!

    Icon IFA

Crimean-Congo haemorrhagic fever virus

  • ELISA

    • Anti-Crimean-Congo fever virus (CCHFV) ELISA (IgG) EI 279a-9601 G
      → Data sheet (PDF)
    • Anti-Crimean-Congo fever virus (CCHFV) ELISA (IgM) EI 279a-9601 M
      → Data sheet (PDF)

    Icon ELISA

Find out more about our test portfolio

Infections

 
 

EUROIMMUN's solutions for infection diagnostics

in Europe

 
 

More information

Contact

If you have any questions, please do not hesitate to contact us:

Product Management Infection Diagnostics

infection-pm(at)euroimmun.de

Or get in touch with your local contact person

Find your local distributor

 

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