MTB

EURORealTime MTB

Evaluation by means of EURORealTime Analysis software
Evaluation by means of EURORealTime Analysis software

With an estimated 10 million new infections per year, tuberculosis is one of the most frequent infectious diseases worldwide. It is caused by pathogens of the Mycobacterium tuberculosis complex (MTBC). This complex encompasses in total eight different mycobacteria, of which seven are described as the causative agents of tuberculosis in humans and animals.

The transmission of the pathogens is primarily aerogenic. Infected persons secrete the pathogenic bacteria in aerosols when coughing or speaking. In immunocompetent patients, tuberculosis proceeds asymptomatically in most cases. A latent infection may persist over decades and be reactivated when the immune system is weakened. In 5 to 10% of patients, active tuberculosis develops. Since the primary way of transmission is via the air, pulmonary tuberculosis manifests in most cases, with bacteria multiplying in the lungs and destroying the lung tissue. In rare cases, tuberculosis can also affect other organs such as the skin or the digestive tract.

The EURORealTime MTB test allows highly specific and sensitive detection of tuberculosis pathogens by means of real-time polymerase chain reaction (real-time PCR). This test system is designed for direct detection of the DNA of all members of the MTBC for tuberculosis diagnostics. It ensures reliable and sensitive identification through the determination of three MTBC-specific DNA target regions. This helps to detect a large number of the existing genetic variations of the MTBC. Direct detection of the pathogens by means of EURORealTime MTB supplements microscopy and detection by culturing and is suited for fast and sensitive tuberculosis diagnostics to support early treatment and prevention of transmission.

Raw data analysis, evaluation, reporting and electronic archiving of the test results can be performed fully automatically using the EURORealTime Analysis software. The software also provides convenient guidance through the entire work procedure, thus preventing the occurrence of errors. The test is extremely simple to perform and does not require in-depth molecular biology knowledge.

ProductOrder number
EURORealTime MTBMP 2145