Cortisol

Cortisol in saliva

The glucocorticoid cortisol is the most important stress hormone in humans. The cortisol concentration follows a typical circadian rhythm. In Cushing’s syndrome the cortisol level is always increased, whereas in Addison’s disease it is low. Mental or physical stress also leads to an increase in free and thus biologically active cortisol.


In chronic stress the increased cortisol production cannot be maintained for very long (non-adaptive stress), resulting in a permanent decrease in the cortisol level. This can be observed in burnout syndrome or chronic fatigue syndrome.

The determination of free cortisol in saliva with the Cortisol Saliva ELISA can be fully automated.

ProductOrder number
Cortisol Saliva ELISAEQ 6141 S