Soluble CD163 (sCD163)

Incubated sCD163 ELISA
  • Reliable, quantitative detection of sCD163 in urine
  • Indication: acute renal ANCA-associated vasculitis, -GBM diseases and -lupus nephritis
  • sCD163 is a non-invasive biomarker which refelcts the Inflammation of the glomeruli (glomerulonephritis) in relation to the migrated M2 macrophages.
  • Increased sCD163 levels in urine are described in patients with active AAV with renal involvement and in patients with active lupus nephritis.
  • Compared to standrad renal inflammatory markers in the diagnostic laboratory (e.g. CRP, hematuria or ANCA titers), the sCD163 level correlates better with the disease activity.
  • Coating: Monoclonal anti-sCD163 antibodies are used for coating and for the detection of sCD163.
sCD163 level in different AAV patients (modified from O´Reilly VP et al., 2016)
ProductOrder number
sCD163 ELISAEQ 6851-U