Preanalytics in dementia diagnostics

Identifying external influencing factors, optimising workflows

The analysis of biomarkers in CSF has in recent years become an important component of Alzheimer's disease diagnostics. In particular, beta-amyloids in CSF are considered excellent biomarkers for amyloid pathology, and their relevance is emphasised in diagnostic guidelines.

Beta-amyloids are, however, subject to preanalytical influences. To understand and recognise these is essential since only careful realisation of each work step from lumbar puncture to CSF analysis can ensure high-quality and thus reliable analysis results.

In the last two decades intensive research has resulted in considerable advances in the understanding of preanalytical impact factors, and the number of published research papers is growing rapidly.

This brochure serves as a compendium for clinicians and laboratory doctors, providing an overview of the current status of preanalytics in Alzheimer's diagnostics. In a white paper, Hugo Vanderstichele, a renowned scientist in the Alzheimer's biomarker community, explains the advances made in recent years that have contributed to a more comparable measurement of Alzheimer's biomarkers today.


Are you interested in our white paper and information brochure?

For your independent professional or commercial activity we would like to offer you our white paper "Paving the road to standardized alzheimer's biomarker measurement" and the brochure "Preanalytics in dementia diagnostics" for free download. On entering your personal data and giving your consent to their promotional use you will receive an email containing the download link for the two documents. In return for the receipt of the documents we will obtain your data for promotional use. Both the whitepaper and brochure may only be used for your own professional training and must not be forwarded to third parties. The offer does not include the download of the whitepaper and the brochure without the enty of your data or your consent to their promotional use.

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