Insect venoms

Clinical significance

Localised pain, swelling, itching and redness occur as normal reactions to an insect bite. However, allergic reactions may occur within minutes or even only hours after the bite.

Symptoms reach from skin reactions with hives, swelling, itching and redness (also at other loci than the bite site) to severe systemic reactions, presenting as swelling of throat and tongue, dyspnoea, nausea, intestinal and stomach complaints, diarrhoea, neurological complaints with states of confusion, vertigo, disturbed gait, increased pulse and drop in blood pressure. In the worst case, the reaction may lead to a life-threatening anaphylactic shock. According to estimations, insect venom allergies occur in approximately 1 to 7% of the population.

Diagnostics

For clarification of insect venom allergies, differential diagnostics are recommended which facilitate exact definition of the allergy-inducing species. EUROIMMUN offers different insect venoms profiles (EUROLINE) which cover the most common causative agents of insect venom allergies. In addition to the natural insect venom extracts, the profiles also encompass recombinant country-specific allergen components (defined partial allergen diagnostics (DPA-Dx) for simultaneous in vitro determination of human IgE antibodies.

In addition, the total IgE concentration in the serum can be determined using the Total IgE ELISA.

 

EUROAssay products are only available in Germany.

Selected Products

Method
Parameter
Substrate
Species
EUROLINE
insect venoms
(i1, i3, CCD)
membrane strip with allergens
(EUROLINE)
ELISA
total IgE
antigen-coated
microplate wells
EUROLINE
DPA-Dx insect venoms 2
(i1, i208, i213, i216, i3, i209, i211, CCD)
membrane strip with allergens
(EUROLINE)
EUROASSAY
DPA-Dx insect venoms 3
(i1, i3, i75, i208, i213, i216, i209, i211, CCD)
EUROASSAY strip
with allergens
EUROLINE
DPA-Dx insect venoms 3
(i1, i3, i75, i208, i213, i216, i209, i211, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
DPA-Dx insect venoms "Southern Europe 1"
(i1, i3, i75, i77, i208, i213, i216, i210, i209, i220, i211, CCD)
membrane strip with allergens
(EUROLINE)
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