Vaccine-preventable diseases

Clinical information

Vaccines help prevent infections, transmission and thus the spread of diseases or pathogens such as tetanus, diphtheria, Bordetella pertussis, tick-borne encephalitis virus (TBE), measles virus, rubella virus or varicella zoster virus (VZV).

Diagnostics

Detection of IgG antibodies in order to assess the immune status is only possible for some pathogens. This requires, e.g. standardised antibody detection based on international reference preparations and the availability of a cut-off to distinguish between existing or non-existent immunity. These values have been described for tetanus, diphtheria, measles, rubella, VZV and TBE. For mumps and pertussis, however, there are no values or markers for immunity known to correspond with immune protection.

Selected Products

Method
Parameter
Substrate
Species
ELISA
diphtheria toxoid
antigen-coated
microplate wells
IIFT
antibodies against Bordetella pertussis
IgA positive control
IIFT
antibodies against Bordetella pertussis
IgG positive control
IIFT
antibodies against Bordetella pertussis
IgM positive control
IIFT
Bordetella pertussis/parapertussis
negative control
EUROLINE
positive control serum: IgG, human, 50x concentrated
for Bordetella pertussis
EUROLINE
Bordetella pertussis
(FHA, PT, ACT separately)
EUROLINE
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Bordetella
pertussis
bacterial
smear
Bordetella
pertussis
IIFT
Bordetella pertussis
Bordetella parapertussis
bacterial
smears
(2 BIOCHIPs per field)
B. pertussis
B. parapertussis
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ELISA
Bordetella
pertactin
antigen-coated
microplate wells
IIFT
antibodies against Bordetella parapertussis
IgA positive control
IIFT
antibodies against Bordetella parapertussis
IgG positive control
IIFT
antibodies against Bordetella parapertussis
IgM positive control
IIFT
Bordetella
parapertussis
bacterial
smear
Bordetella
parapertussis
ELISA
tetanus toxoid
antigen-coated
microplate wells
EUROArray
EUROArray HPV
IIFT
antibodies against Rubella virus
IgG positive control
IIFT
high-avid antibodies against Rubella virus
IgG positive control
IIFT
low-avid antibodies against Rubella virus
IgG positive control
IIFT
Rubella virus
negative control
WESTERNBLOT
Rubella virus
Westernblot
whole antigen
ELISA
Rubella virus
antigen-coated
microplate wells
ELISA
Rubella virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Rubella virus
infected cells
EU 13
ELISA
Rubella virus
avidity determination
antigen-coated
microplate wells
ELISA
Rubella virus glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Rubella virus (IgG)
ELISA
Rubella virus
antibody determination in CSF
antigen-coated
microplate wells
IIFT
antibodies against Measles virus
IgG positive control
IIFT
antibodies against Measles virus
IgM positive control
IIFT
Measles virus
negative control
ELISA
Measles virus
antigen-coated
microplate wells
ELISA
Measles virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Measles virus
infected cells
EU 38
ELISA
Measles virus
avidity determination
antigen-coated
microplate wells
ELISA
Measles virus NP: recombinant nucleoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Measles virus (IgG)
ELISA
Measles virus
antibody determination in CSF
antigen-coated
microplate wells
IIFT
antibodies against Mumps virus
IgG positive control
IIFT
antibodies against Mumps virus
IgM positive control
IIFT
Mumps virus
negative control
ELISA
Mumps virus
antigen-coated
microplate wells
ELISA
Mumps virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Mumps virus
infected cells
EU 13
IIFT
Mumps virus
infected cells
EU 38
ELISA
Mumps virus AT: strains "Enders"
and "Jeryl Lynn"
antigen-coated
microplate wells
ELISA
Mumps virus G5: native antigens,
genotype "G5"
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Mumps virus (IgG)
ELISA
Mumps virus
antibody determination in CSF
antigen-coated
microplate wells
IIFT
antibodies against Varicella zoster virus (VZV)
IgA positive control
IIFT
antibodies against Varicella zoster virus (VZV)
IgG positive control
IIFT
high-avid antibodies against Varicella zoster virus (VZV)
IgG positive control
IIFT
antibodies against Varicella zoster virus (VZV)
IgM positive control
IIFT
low-avid antibodies against Varicella zoster virus (VZV)
IgG positive control
IIFT
Varicella zoster virus (VZV)
negative control
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Varicella zoster virus
(VZV)
infected cells
EU 168
ELISA
Varicella zoster virus (VZV)
avidity determination
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV) glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-VZV (IgG)
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
IIFT
antibodies against TBE virus (TBEV)
IgG positive control
IIFT
antibodies against TBE virus (TBEV)
IgM positive control
IIFT
TBE virus (TBEV)
negative control
ELISA
TBE virus
antigen-coated
microplate wells
ELISA
TBE virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
TBE virus (TBEV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
antibodies against Flaviviruses
IgG positive control
IIFT
Flaviviruses
negative control
ELISA
TBE virus
avidity determination
antigen-coated
microplate wells
IIFT
Flavivirus Mosaic 1
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
4 BIOCHIPs per field:
infected cells
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
EU 14
IIFT
Flavivirus Profile 2
upper row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
bottom row:
Dengue virus
types 1 - 4 (DENV)


infected cells
infected cells
infected cells
infected cells

infected cells


EU 14
EU 14
EU 14
EU 14

EU 14
IIFT
Flavivirus Mosaic 3
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
Dengue virus types 1 - 4 (DENV)
9 BIOCHIPs per field:
infected cells
infected cells
infected cells
infected cells
infected cells
non-infected cells

EU 14
EU 14
EU 14
EU 14
EU 14
EU 14
ELISA
CSQ pair of controls
anti-TBE virus Vienna (IgG)
ELISA
TBE virus
Vienna
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-TBE virus (IgG)
ELISA
CSQ pair of controls
anti-TBE virus (IgM)
ELISA
TBE virus
antibody determination in CSF
antigen-coated
microplate wells
IIFT
antibodies against Influenza virus type A
IgA positive control
IIFT
antibodies against Influenza virus type A
IgG positive control
IIFT
antibodies against Influenza virus type A
IgM positive control
IIFT
Influenza virus type A/B
negative control
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type A
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Influenza virus type A
infected cells
EU 50
IIFT
Influenza virus type A
Influenza virus type B
infected cells
infected cells
(2 BIOCHIPs per field)
EU 50
EU 50
IIFT
antibodies against Influenza virus type B
IgA positive control
IIFT
antibodies against Influenza virus type B
IgG positive control
IIFT
antibodies against Influenza virus type B
IgM positive control
ELISA
Influenza virus type B
antigen-coated
microplate wells
ELISA
Influenza virus type B
antigen-coated
microplate wells
ELISA
Influenza virus type B
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Influenza virus type B
infected cells
EU 13
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