Respiratory infections

Clinical information

Infections of the respiratory tract are mainly caused by viruses (e.g. influenza viruses, adenoviruses, RSV), but also bacteria (e.g. Legionella, Bordetella pertussis, Mycoplasma pneumoniae, Chlamydia pneumoniae).  Both the upper (e.g. nasal mucosa, paranasal sinuses) and the lower respiratory tracts (airways and bronchia) can be affected. The pathogens are mainly transmitted by droplet infection. Symptoms of respiratory infections include fever, cough, headaches and pain, pharyngitis, sinusitis, bronchitis or pneumonia.

Diagnostics

Since many respiratory pathogens cause similar symptoms, the diseases cannot usually be diagnosed based on the clinical image alone. Consequently, laboratory diagnostics are particular valuable. Direct pathogen detection (e.g. PCR) is in most cases the method of choice for the detection of acute respiratory infections.
Since antibodies are only formed some days or weeks following infection and the prevalence increases with age, an infection can often only be diagnosed retrospectively by investigation of a serum pair and detection of an IgG titer increase. Serological tests can also contribute to epidemiological monitoring.

Selected Products

Method
Parameter
Substrate
Species
IIFT
antibodies against Bordetella pertussis
IgA positive control
IIFT
antibodies against Bordetella pertussis
IgG positive control
IIFT
antibodies against Bordetella pertussis
IgM positive control
IIFT
Bordetella pertussis/parapertussis
negative control
EUROLINE
positive control serum: IgG, human, 50x concentrated
for Bordetella pertussis
EUROLINE
Bordetella pertussis
(FHA, PT, ACT separately)
EUROLINE
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Bordetella
pertussis
bacterial
smear
Bordetella
pertussis
IIFT
Bordetella pertussis
Bordetella parapertussis
bacterial
smears
(2 BIOCHIPs per field)
B. pertussis
B. parapertussis
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ELISA
Bordetella
pertactin
antigen-coated
microplate wells
IIFT
antibodies against Bordetella parapertussis
IgA positive control
IIFT
antibodies against Bordetella parapertussis
IgG positive control
IIFT
antibodies against Bordetella parapertussis
IgM positive control
IIFT
Bordetella
parapertussis
bacterial
smear
Bordetella
parapertussis
IIFT
antibodies against Legionella pneumophila serotypes 1 or 4
IgAGM positive control
ELISA
Legionella pneumophila
antigen-coated
microplate wells
ELISA
Legionella pneumophila
antigen-coated
microplate wells
ELISA
Legionella pneumophila
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
BIOCHIP Sequence
Legionella pneumophila
serotypes 1 - 14
bacterial smears
(1 BIOCHIP
per serotype)
verification BIOCHIP
Legionella
pneumophila
IIFT
Legionella pneumophila
mixture 1-4-6-8
mixture 2-3-5-7
mixture 9-11-13
mixture 10-12-14
bacterial
smears
verification BIOCHIP
(5 BIOCHIPs per field)
Legionella
pneumophila
IIFT
antibodies against Legionella pneumophila mixture 1-2-3-4-5-6-7,
mixture 8-9-10-11-12-13-14, mixture L. non-pneumophila 6 sp
IgG positive control
IIFT
Legionella Mosaic 4
L. pneumophila mixture 5 (serotype 1-7)
L. pneumophila mixture 6 (serotype 8-14)
L. non pneumophila mixture 7
4 BIOCHIPs per field:
bacterial smear
bacterial smear
bacterial smear
verification BIOCHIP

L. pneumophila
L. pneumophila
6 L. non-pneum. sp.
IIFT
Legionella pneumophila/non-pneumophila
negative control
IIFT
antibodies against Legionella pneumophila mixture 1-4-6-8
IgAGM positive control
IIFT
Legionella pneumophila
mixture 1-4-6-8
bacterial
smear
verification BIOCHIP
(2 BIOCHIPs per field)
Legionella
pneumophila
IIFT
Legionella pneumophila
mixture 1-4-6-8
mixture 2-3-5-7

bacterial
smears
verification BIOCHIP
(3 BIOCHIPs per field)

Legionella
pneumophila
IIFT
antibodies against Legionella jordanis
IgAGM positive control
IIFT
antibodies against Legionella longbeachae
IgG positive control
IIFT
Mosaic Legionella non-
pneumophila
Legionella jordanis
Legionella bozemanii
Legionella gormanii
Legionella micdadei
Legionella dumoffii
Legionella longbeachae
6 BIOCHIPs per field:

bacterial
smears


L. jordanis
L. bozemanii
L. gormanii
L. micdadei
L. dumoffii
L. longbeachae
IIFT
antibodies against Mycoplasma pneumoniae
IgG positive control
IIFT
antibodies against Mycoplasma pneumoniae
IgM positive control
ELISA
Mycoplasma pneumoniae
antigen-coated
microplate wells
ELISA
Mycoplasma pneumoniae
antigen-coated
microplate wells
ELISA
Mycoplasma pneumoniae
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Mycoplasma
pneumoniae
bacteria
Mycoplasma
pneumoniae
IIFT
Mycoplasma
pneumoniae
EUROPattern
bacteria
Mycoplasma
pneumoniae
IIFT
MERS-CoV, SARS-CoV
negative control
IIFT
SARS coronavirus
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
ELISA
MERS coronavirus
antigen-coated
microplate wells
IIFT
MERS coronavirus
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
ELISA
SARS-CoV-2
antigen-coated
microplate wells
PCR
EURORealTime SARS-CoV-2
ELISA
SARS-CoV-2 QuantiVac
ELISA
SARS-CoV-2 NCP
IIFT
antibodies against Respiratory syncytial virus (RSV)
IgA positive control
IIFT
antibodies against Respiratory syncytial virus (RSV)
IgG positive control
IIFT
antibodies against Respiratory syncytial virus (RSV)
IgM positive control
IIFT
Respiratory syncytial virus (RSV)
negative control
ELISA
Respiratory syncytial virus
(RSV)
antigen-coated
microplate wells
ELISA
Respiratory syncytial virus
(RSV)
antigen-coated
microplate wells
ELISA
Respiratory syncytial virus (RSV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Respiratory syncytial virus
(RSV)
infected cells
EU 38
IIFT
antibodies against Adenovirus
IgA positive control
IIFT
antibodies against Adenovirus
IgG positive control
IIFT
antibodies against Adenovirus
IgM positive control
IIFT
Adenovirus
negative control
ELISA
Adenovirus
antigen-coated
microplate wells
ELISA
Adenovirus
antigen-coated
microplate wells
ELISA
Adenovirus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Adenovirus
type 3
infected cells
EU 38
IIFT
antibodies against Influenza virus type A
IgA positive control
IIFT
antibodies against Influenza virus type A
IgG positive control
IIFT
antibodies against Influenza virus type A
IgM positive control
IIFT
Influenza virus type A/B
negative control
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type A
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Influenza virus type A
infected cells
EU 50
IIFT
Influenza virus type A
Influenza virus type B
infected cells
infected cells
(2 BIOCHIPs per field)
EU 50
EU 50
IIFT
antibodies against Influenza virus type B
IgA positive control
IIFT
antibodies against Influenza virus type B
IgG positive control
IIFT
antibodies against Influenza virus type B
IgM positive control
ELISA
Influenza virus type B
antigen-coated
microplate wells
ELISA
Influenza virus type B
antigen-coated
microplate wells
ELISA
Influenza virus type B
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Influenza virus type B
infected cells
EU 13
IIFT
antibodies against Parainfluenza virus types 1 - 4
IgA positive control
IIFT
antibodies against Parainfluenza virus types 1 - 4
IgG positive control
IIFT
antibodies against Parainfluenza virus types 1 - 4
IgM positive control
IIFT
Parainfluenza virus
negative control
ELISA
Parainfluenza virus
types 1 - 4 (Pool)
antigen-coated
microplate wells
ELISA
Parainfluenza virus
types 1 - 4 (Pool)
antigen-coated
microplate wells
ELISA
Parainfluenza virus types 1 - 4
(Pool) incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Mosaic Parainfluenza virus
types 1 - 4
4 BIOCHIPs per field:
infected cells

EU 18/9
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