Gastrointestinal infections

Clinical information

Gastrointestinal infections can be caused by bacteria, viruses and parasites and are among the most frequent infectious diseases. They manifest as gastritis, diarrhoea, vomiting or unspecific symptoms which occur within only few hours after uptake of the pathogen with some bacterial or viral infections and may, in rare cases, lead to chronic sequelae. Infections with parasitic pathogens, however, usually take a chronic course.

Diagnostics

Viral infections are often self-limiting, which is why it is sufficient to treat the symptoms, and laboratory diagnostic tests are usually not performed. Bacteria such as Yersinia and Campylobacter, however, may cause immunologically mediated secondary diseases, e.g. reactive arthritis. Here, serological tests may support the diagnosis. Infections with Helicobacter pylori may cause chronic active gastritis and complications such as gastroduodenal ulcer disease, stomach carcinoma or lymphoma. Antibody detection is recommended in suspected cases of non-acute or chronic infection. Parasitic pathogens such as Schistosoma and Strongyloides stercoralis can also cause gastrointestinal symptoms with chronic courses. Direct and indirect methods are applied for diagnostics. In general, specific antibody detection is suitable to support the diagnosis in suspected cases of chronic courses or secondary diseases, but not for diagnostics in acute cases.

Selected Products

Method
Parameter
Substrate
Species
WESTERNBLOT
antibodies against Helicobacter pylori
IgA positive control
WESTERNBLOT
antibodies against Helicobacter pylori
IgG positive control
ELISA
Helicobacter pylori
antigen-coated
microplate wells
ELISA
Helicobacter pylori
antigen-coated
microplate wells
WESTERNBLOT
EUROLINE-WB
Helicobacter pylori
Westernblot
whole antigen of H. pylori,
plus recombinant VacA and CagA antigen
ELISA
Helicobacter pylori
(CagA)
antigen-coated
microplate wells
ELISA
Helicobacter pylori
(CagA)
antigen-coated
microplate wells
ELISA
Campylobacter jejuni
antigen-coated
microplate wells
ELISA
Campylobacter jejuni
antigen-coated
microplate wells
IIFT
Listeria monocytogenes
negative control
IIFT
antibodies against Listeria monocytogenes 1/2a
IgG positive control
IIFT
antibodies against Listeria monocytogenes 1/2a
IgM positive control
IIFT
Listeria
monocytogenes
1/2a and 4b
bacterial
smears
(2 BIOCHIPs per field)
Listeria
monocytogenes
1/2a and 4b
IIFT
antibodies against Listeria monocytogenes 4b
IgG positive control
PCR
EURORealTime MTB
WESTERNBLOT
antibodies against Yersinia enterocolitica
IgA positive control
(for diagnosing various forms of arthritis)
WESTERNBLOT
antibodies against Yersinia enterocolitica
IgG positive control
(for diagnosing various forms of arthritis)
EUROLINE
Yersinia enterocolitica
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
EUROLINE
WESTERNBLOT
Yersinia enterocolitica
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
Westernblot
isolated virulence factors
(release proteins, Yop)
of Yersinia enterocolitica
ELISA
Yersinia enterocolitica
antigen-coated
microplate wells
ELISA
Yersinia enterocolitica
antigen-coated
microplate wells
ELISA
Strongyloides
antigen-coated
microplate wells
IIFT
antibodies against Schistosoma mansoni
IgG positive control
IIFT
antibodies against Schistosoma mansoni
IgM positive control
IIFT
Schistosoma mansoni
negative control
ELISA
Schistosoma
antigen-coated
microplate wells
ELISA
Schistosoma
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Schistosoma
mansoni
frozen
sections
Schistosoma
mansoni, adult
IIFT
antibodies against Adenovirus
IgA positive control
IIFT
antibodies against Adenovirus
IgG positive control
IIFT
antibodies against Adenovirus
IgM positive control
IIFT
Adenovirus
negative control
ELISA
Adenovirus
antigen-coated
microplate wells
ELISA
Adenovirus
antigen-coated
microplate wells
ELISA
Adenovirus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Adenovirus
type 3
infected cells
EU 38
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