Emerging diseases

Clinical information

The term tropical diseases encompasses a range of infectious diseases, which – as the name suggests – originate in tropical regions. However, they can also occur in other regions, for example, through transmission by returning travellers. Emerging diseases are infections that are new in a population, or are already known but have increased rapidly in incidence or regional distribution. Mosquito-borne viruses such as Zika, dengue and chikungunya viruses generally cause febrile diseases with unspecific flu-like symptoms. In the further course of disease, severe complications such as encephalitis or haemorrhaging can occur. Moreover, neurological abnormalities in newborns are associated with Zika virus infection. In addition to viral diseases, parasitic infections, for example with Echinococcus, Plasmodium, Strongyloides, Trypanosoma or Schistosoma, also play a role in humans. The symptoms of a parasitic infection are extremely variable and sometimes occur after months or years, as is the case with echinococcosis.

Diagnostics

The diagnosis of tropical infections is a particular challenge. Over the past years it has been observed that many new viruses and other pathogens have spread worldwide, introducing unknown diseases into previously unaffected regions. For these parameters there are often no commercial diagnostic test systems available. Antibody analysis is useful for testing travellers after trips to endemic areas and for screening large population groups.

Selected Products

Method
Parameter
Substrate
Species/ Antigen
IIFT
MERS-CoV, SARS-CoV
negative control
IIFT
SARS coronavirus
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
MERS coronavirus
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
ELISA
MERS coronavirus
antigen-coated
microplate wells
recombinant S1 antigen
of MERS coronavirus
(MERS-CoV S1)
ELISA
SARS-CoV-2
antigen-coated
microplate wells
recombinant S1 antigen
of SARS-CoV-2
PCR
EURORealTime SARS-CoV-2
ELISA
SARS-CoV-2 NCP
IIFT
antibodies against TBE virus (TBEV)
IgG positive control
IIFT
antibodies against TBE virus (TBEV)
IgM positive control
IIFT
TBE virus (TBEV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
TBE virus (TBEV)
negative control
ELISA
TBE virus
antigen-coated
microplate wells
TBE viral proteins
(strain "K23")
ELISA
TBE virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
TBE viral proteins
(strain "K23")
IIFT
antibodies against Flaviviruses
IgG positive control
IIFT
Flavivirus Mosaic 1
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
4 BIOCHIPs per field:
infected cells
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
EU 14
IIFT
Flaviviruses
negative control
ELISA
TBE virus
avidity determination
antigen-coated
microplate wells
TBE viral proteins
(strain "K23")
IIFT
Flavivirus Profile 2
upper row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
bottom row:
Dengue virus
types 1 - 4 (DENV)


infected cells
infected cells
infected cells
infected cells

infected cells


EU 14
EU 14
EU 14
EU 14

EU 14
IIFT
Flavivirus Mosaic 3
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
Dengue virus types 1 - 4 (DENV)
9 BIOCHIPs per field:
infected cells
infected cells
infected cells
infected cells
infected cells
non-infected cells

EU 14
EU 14
EU 14
EU 14
EU 14
EU 14
ELISA
CSQ pair of controls
anti-TBE virus Vienna (IgG)
ELISA
TBE virus
Vienna
antigen-coated
microplate wells
TBE viral proteins
(strain "K23")
ELISA
CSQ pair of controls
anti-TBE virus (IgG)
ELISA
CSQ pair of controls
anti-TBE virus (IgM)
ELISA
TBE virus
antibody determination in CSF
antigen-coated
microplate wells
TBE viral proteins
(strain "K23")
IIFT
antibodies against West Nile virus (WNV)
IgG positive control
IIFT
antibodies against West Nile virus (WNV)
IgM positive control
IIFT
low-avid antibodies against West Nile virus (WNV)
IgG positive control
IIFT
West Nile virus (WNV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
West Nile virus (WNV)
negative control
ELISA
West Nile virus (WNV)
antigen-coated
microplate wells
detergent-extracted glycoprotein E
from the membrane fraction of human cells
ELISA
West Nile virus (WNV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
detergent-extracted glycoprotein E
from the membrane fraction of human cells
ELISA
West Nile virus (WNV)
avidity determination
antigen-coated
microplate wells
detergent-extracted glycoprotein E
from the membrane fraction of human cells
IIFT
antibodies against Japanese encephalitis virus (JEV)
IgG positive control
IIFT
antibodies against Japanese encephalitis virus (JEV)
IgM positive control
IIFT
Japanese encephalitis virus (JEV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Japanese encephalitis virus (JEV)
negative control
ELISA
Japanese encephalitis virus (JEV)
antigen-coated
microplate wells
detergent-extracted glycoprotein E
from the membrane fraction of human cells
ELISA
Japanese encephalitis virus (JEV)
antigen-coated
microplate wells
detergent-extracted glycoprotein E
from the membrane fraction of human cells
IIFT
antibodies against Yellow fever virus (YFV)
IgG positive control
IIFT
antibodies against Yellow fever virus (YFV)
IgM positive control
IIFT
Yellow fever virus (YFV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Yellow fever virus (YFV) EUROPattern
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Yellow fever virus (YFV)
negative control
ELISA
Usutu virus
antigen-coated
microplate wells
recombinant glycoprotein E
of Usutu virus
IIFT
Zika virus (ZIKV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Zika virus (ZIKV) EUROPattern
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
ELISA
Zika virus (ZIKV)
antigen-coated
microplate wells
recombinant NS1 antigen
from Zika virus
ELISA
Zika virus (ZIKV)
antigen-coated
microplate wells
recombinant NS1 antigen
from Zika virus
ELISA
Zika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant NS1 antigen
from Zika virus
ELISA
Zika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
specific NS1 antigen
from Zika virus
PCR
EURORealTime Zika Virus
IIFT
Arbovirus Fever Mosaic 2 EUROPattern
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
IIFT
Arbovirus Fever Mosaic 2
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
IIFT
Arbovirus Profile 3
upper row :
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
bottom row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)


infected cells
infected cells
infected cells

infected cells
infected cells
infected cells
infected cells


EU 14
EU 14
EU 14

EU 14
EU 14
EU 14
EU 14
IIFT
antibodies against Dengue virus (DENV)
IgG positive control
IIFT
antibodies against Dengue virus (DENV)
IgM positive control
IIFT
Dengue virus (DENV)
negative control
IIFT
Mosaic Dengue virus
types 1 - 4 (DENV)
4 BIOCHIPs per field:
infected cells

EU 14
IIFT
Mosaic Dengue virus
types 1 - 4 (DENV) EUROPattern
4 BIOCHIPs per field:
infected cells

EU 14
ELISA
Dengue virus (DENV)
type 1-4
antigen-coated
microplate wells
preparation of Dengue
virus particles and recombinant
glycoprotein E of types 1-4
ELISA
Dengue virus (DENV)
type 1-4
incl. IgG/RF absorbent
antigen-coated
microplate wells
preparation of Dengue
virus particles and recombinant
glycoprotein E of types 1-4
ELISA
Dengue virus NS1
(DENV)
antibody-coated
microplate wells
Dengue virus NS1 (type 1-4)
ELISA
Dengue virus NS1 (DENV)
type 1-4
antigen-coated
microplate wells
recombinant NS1 antigen
from Dengue virus
ELISA
Dengue virus (DENV)
antigen-coated
microplate wells
preparation of
Dengue virus particles
ELISA
Dengue virus (DENV)
antigen-coated
microplate wells
preparation of
Dengue virus particles
ELISA
Dengue virus (DENV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
preparation of
Dengue virus particles
IIFT
antibodies against Sandfly fever virus
IgG positive control
IIFT
antibodies against Sandfly fever virus
IgM positive control
IIFT
Sandfly fever virus Mosaic 1
EUROPattern
types Sicilian, Naples,
Toscana, Cyprus
4 BIOCHIPs per field:

infected cells


EU 14
IIFT
Sandfly fever virus Mosaic 1
types Sicilian, Naples,
Toscana, Cyprus
4 BIOCHIPs per field:
infected cells

EU 14
IIFT
Sandfly fever virus
negative control
ELISA
Toscana virus
antigen-coated
microplate wells
recombinant
N-protein from Toscana virus
IIFT
antibodies against Hantavirus
IgG positive control
IIFT
antibodies against Hantavirus
IgM positive control
IIFT
Hantavirus Mosaic 1 EUROPattern
types Hantaan (HTNV), Sin Nombre (SNV),
Puumala (PUUV), Dobrava (DOBV),
Seoul (SEOV), Saaremaa (SAAV)
6 BIOCHIPs per field:
infected cells

EU 14
IIFT
Hantavirus Mosaic 1
types Hantaan, Sin Nombre, Puumala,
Dobrava, Seoul, Saaremaa
6 BIOCHIPs per field:
infected cells

EU 14
IIFT
Hantavirus
negative control
ELISA
Hantavirus Pool 1 "Eurasia"
antigen-coated
microplate wells
recombinant
nucleocapsid proteins from strains
Hantaan HTNV Fojnica,
Dobrava DOBV Slovenia,
Puumala PUUV Vranica
ELISA
Hantavirus Pool 1 "Eurasia"
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant
nucleocapsid proteins from strains
Hantaan HTNV Fojnica,
Dobrava DOBV Slovenia,
Puumala PUUV Vranica
EUROLINE
Hantavirus Profile 1
(PUUV, DOBV, HTNV separately)
EUROLINE
IIFT
Hantavirus Mosaic 2 Eurasia
types Hantaan, Puumala,
Dobrava, Seoul, Saaremaa
6 BIOCHIPs per field:
infected and non-
infected cells

EU 14
ELISA
Hantavirus Pool 2 "America"
antigen-coated
microplate wells
recombinant
nucleocapsid proteins from strains
Andes ANDV and Sin Nombre SNV
ELISA
Hantavirus Pool 2 "America"
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant
nucleocapsid proteins from strains
Andes ANDV and Sin Nombre SNV
EUROLINE
Hantavirus Profile GLOBAL
(PUUV, DOBV, HTNV, SEOV, SNV, ANDV separately)
EUROLINE
IIFT
Hantavirus Mosaic 3: America EUROPattern
types Sin Nombre, Andes
2 BIOCHIPs per field:
infected cells

EU 14
IIFT
Hantavirus Mosaic 3: America
types Sin Nombre, Andes
2 BIOCHIPs per field:
infected cells

EU 14
IIFT
antibodies against Crimean Congo fever virus (CCHFV)
IgG positive control
IIFT
antibodies against Crimean Congo fever virus (CCHFV)
IgM positive control
IIFT
Crimean Congo fever virus (CCHFV)
negative control
IIFT
Crimean Congo fever virus Mosaic 2
CCHFV-GPC
CCHFV-N
3 BIOCHIPs per field:
transfected cells
transfected cells
control transfection

EU 90
EU 90
EU 90
IIFT
Rift Valley fever virus (RVFV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Rift Valley fever virus (RVFV)
negative control
IIFT
antibodies against Chikungunya virus (CHIKV)
IgG positive control
IIFT
antibodies against Chikungunya virus (CHIKV)
IgM positive control
IIFT
Chikungunya virus (CHIKV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Chikungunya virus (CHIKV) EUROPattern
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Chikungunya virus (CHIKV)
negative control
ELISA
Chikungunya virus (CHIKV)
antigen-coated
microplate wells
recombinant structural protein
from Chikungunya virus
ELISA
Chikungunya virus (CHIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
recombinant structural protein
from Chikungunya virus
IIFT
Arbovirus Fever Mosaic 1
Chikungunya virus (CHIKV)
Japanese encephalitis virus (JEV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
ELISA
Mayaro virus (MAYV)
antigen-coated
microplate wells
recombinant structural protein
from Mayaro virus
ELISA
Mayaro virus (MAYV)
antigen-coated
microplate wells
recombinant structural protein
from Mayaro virus
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