Calcitonin

Calcitonin

Calcitonin is the antagonist of parathyroid hormone in the regulation of calcium metabolism. Its production in the parathyroid glands and secretion of calcitonin is stimulated by an elevated calcium level and results in a reduction in the calcium concentration in the blood. Calcitonin inhibits osteoclast activity, and too low calcitonin levels are associated with oseopenia, a preliminary stage of osteoporosis. For this reason calcitonin is one of the substances given in osteoporosis therapy.

Calcitonin serodiagnostics is employed for clarification of scintigraphically cold thyroid nodules and for post-operative monitoring after removal of C-cell carcinoma. The serum calcitonin level is strongly increased in medullary thyroid carcinoma (C-cell carcinoma).

The quantitative determination of calcitonin in serum with the Calcitonin ELISA can be fully automated.

ProductOrder number
Calcitonin ELISAEQ 6431

Radioimmunoassays (RIA/IRMA): Thyroid-specific autoantibodies, antigens and hormones

Radioimmunoassays (RIA) for the diagnosis of thyroid diseases
  • Monospecific determination of autoantibodies against thyroglobulin (TG), thyroid peroxidase (TPO) and thyrotropin receptors (TSH-R).
  • Specific determination of the thyroid antigen thyrotropin and the hormones free triiodothyronine, (FT3), free thyroxine (FT4), thyrotropin (TSH), calcitonin.
  • Indication: Hashimoto's thyroiditis, Graves' disease, medullary thyroid carcinoma (MTC), thyroidal C-cell hyperplasia, therapy monitoring in hyperthyrosis and hypothyrosis.
  • Serum dilutions: 1:50 in anti-TG and anti-TPO (magnetic), 1:20 in anti-TG and anti-TPO (precipitation), undiluted in all other test kits.
  • 5-point to 8-point calibration (quantitative).
ProductOrder number
Calcitonin RD 1019