HSV-1/2

EURORealTime HSV-1/2

Evaluation with EURORealTime Analysis software
Evaluation with EURORealTime Analysis software

Herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) are worldwide distributed, human pathogenic viruses from the family Herpesviridae. If the lips and facial region are affected, HSV-1 is usually the pathogenic agent while genital infections can be caused by either virus type. In 20% to 30% of cases they are caused by HSV-1.

In primary infections the virus penetrates the mucosal cells, multiplies and is released in ulcers or inflammatory skin blisters. Infections persist lifelong, alternating between asymptomatic and acute phases. In adults, HSV infection may cause encephalitis or meningitis and, in immunodeficient patients, also disseminated infections which may cause lesions at different locations in the skin, or enter into the central nervous system. Alongside mild courses, infections in newborns may also lead to neonatal herpes encephalitis or to disseminated forms. Infections in foetuses often result in intrauterine death, malformations or preterm birth.

The EURORealTime HSV-1/2 test allows highly specific and sensitive detection of HSV-1 and HSV-2 as well as quantification of viral DNA by means of real-time polymerase chain reaction (real-time PCR). The test system allows for the direct detection of HSV-1 and HSV-2 within the framework of diagnostics of sexually transmitted infections and infections causing herpes simplex encephalitis. The molecular genetic detection by means of EURORealTime HSV-1/2 PCR is especially suited for early diagnostics of HSV-1 and -2 infections as well as for differentiation of both types and is significantly faster, compared to detection in culture.

The analysis of raw data, evaluation, creation of reports and electronic archiving can be performed fully automatically by means of the EURORealTime Analysis Software. The standard curves used for the automatic quantification of the viral load can be stored and reused in later runs, if required. Moreover, the software offers convenient guidance through the entire workflow and thus helps to avoid errors. The direct detection of HSV-1 and -2 by means of EURORealTime HSV-1/2 PCR and EURORealTime Analysis Software is extremely easy to perform – no in-depth molecular biological knowledge is required.

ProductOrder number
EURORealTime HSV-1/2MP 2530