Antibodies against herpes simplex virus (HSV)

BIOCHIP Mosaic HSV-1/HSV-2

Antibodies against HSV-1 and HSV-2
  • Sensitive screening test for the detection of antibodies against herpes simplex viruses.
  • Indication: herpes simplex.
  • Initial dilution 1 : 10 (IgM), 1 : 100 (IgG).
  • If antibodies against herpes simplex-2 virus are present in the sample, a typical fluorescence of the infected cells is obtained – mainly in the cytoplasm, less in the cell nuclei.
  • As HSV-1 and HSV-2 are morphologically and immunologically closely related, cross-reactions can occur. Differentiation may be attempted by testing a serum against both antigen substrates and comparing the titers.
  • The BIOCHIP Mosaic™ can be supplemented as required with further substrates, e.g. other infectious agents.
  • Anti-HSV individual tests for indirect immunofluorescence:

ProductOrder number
Anti-HSV-1 IIFT (IgG / IgM)FI 2531 G / M
Anti-HSV-2 IIFT (IgG / IgM)FI 2532 G / M
BIOCHIP Mosaic HSV-1/HSV-2 (IgG / IgM)FI 2531-1 G / M

Anti-HSV-1, anti-HSV-2

Incubated Anti-HSV-1 ELISA
  • Specific confirmatory tests for antibodies against HSV-1 or HSV-2.
  • Indication: herpes simplex.
  • Serum dilution 1 : 101; conjugate class anti-IgG or anti-IgM, POD-labelled.
  • 1-point calibration, semiquantitative (IgM) or 3-point calibration, quantitative (IgG). Identical incubation conditions and times: all tests can be combined without difficulty on one and the same microplate.
  • Antigens: type-specific glycoproteins C1 or G2. Cross-reactions do not occur.
  • IgM test kit includes IgG/RF absorbent in sample buffer for IgG absorption in preparation for the determination of specific IgM class antibodies.
  • Available individual ELISA:

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ProductOrder number
Anti-HSV-1 ELISAEI 2531-2 G / M
Anti-HSV-2 ELISAEI 2532-2 G / M
Anti-HSV-1/2-Pool ELISAEI 2531-1 A / G / M

EUROLINE-WB: anti-HSV

Incubated Anti-HSV EUROLINE-WB
  • Specific confirmatory test for the differentiation of antibodies against HSV-1 and HSV-2.
  • Indication: herpes simplex.
  • Serum dilution 1 : 51; conjugate class anti-IgG or anti-IgM, AP-labelled.
  • EUROLINE-WB is a combination of westernblot and line blot techniques. Proteins from an SDS extract of HSV-1 are electrophoretically separated according to molecular mass and transferred onto a nitrocellulose membrane. A membrane chip coated with HSV-2 type-specific glycoprotein G2 (gG 2), purified by affinity chromatography, is then added to the westernblot strips.
  • Bands from all specific antigens are included and clearly separated.
  • The gG 2 band allows the simple differentiation between HSV-1 and HSV-2 infections.
  • Test strips can be automatically incubated and evaluated using the systems EUROBlotMaster, EUROBlotOne, and EUROLineScan.

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    ProductOrder number
     Anti-HSV-1/HSV-2-gG-2 EUROLINE-WB (IgG / IgM) DY 2531-1 G / M

    EUROLINE: TORCH Profile

    • Immunoblot profiles for the determination of specific antibodies against pregnancy-relevant infectious agents: Toxoplasma gondii, rubella virus, CMV, HSV-1 and HSV-2, Bordetella pertussis, Chlamydia trachomatis, Parvovirus B19, Treponema pallidum, VZV
    • Multiparameter analysis- up to 10 results per test strip in a single incubation
    • Simple and fast test performance
    • Estimation of vaccination titers and the risks for an existing pregnancy
    • Recombinant and native highly purified antigens for determination of the immune status
    • Guidance for the implementation of further measures to prevent infections or investigations in prenatal care
    ProductOrder number
    EUROLINE Anti-TO.R.C.H. Profile (IgG, IgM)DN 2410-4 G / M
    EUROLINE Anti-TO.R.C.H. 10 Profile (IgG)DN 2410-11 G