Clinical information
Parasites are eukaryotic organisms that live off of their host. These pathogens represent a very heterogeneous group that differs greatly regarding their structures and life cycles. Morphologically, single-cell organisms (protozoa) are distinguished from complex worm structures (helminths). Depending on the stage, helminths can present in several forms such as eggs, larvae, and mature worms. Infections lead to a great variety of symptoms that depend on the causative organism. However, these pathogens do not usually cause life-threatening illness since they are dependent on the host’s fitness. Infections may therefore remain undiscovered for a long time. Emergency diagnostics is generally not indicated, except for suspected cases of acute malaria.
Diagnostics
The diagnosis of parasite infections can be supported by direct and indirect methods. As the use of one single detection method is not reliable due to the mostly highly complex life cycles, different methods such as serology and direct pathogen detection are combined. Especially in the case of travellers’ diarrhoea or chronic diarrhoea direct pathogen detection is used.
| Technology | Parameter | Substrate | Species | Calibration | Ig Class | Format | Order No. |
|---|---|---|---|---|---|---|---|
| ELISA |
CSQ pair of controls anti-Toxoplasma gondii (IgG) |
IgG |
02 x 20 |
CK 2410-0220-L G | |||
| ELISA |
CSF: Anti-Toxoplasma gondii ELISA (IgG ) Sample type: CSF/serum pair |
antigen-coated microplate wells |
native antigens of Toxoplasma gondii |
5/25/50/100 U | IgG |
96 x 01 |
EI 2410-9601-L G |
| IIFT |
Schistosoma mansoni |
frozen sections |
Schistosoma mansoni, adult |
IgG IgM |
10 x 05 10 x 05 |
FI 2300-1005 G FI 2300-1005 M |
|
| ELISA | Anti-Strongyloides ELISA (IgG) |
antigen-coated microplate wells |
native antigens from Strongyloides larvae |
semi-quantitative | IgG |
96 x 01 |
EI 2290-9601 G |
| ELISA | Anti-Schistosoma ELISA (IgG) |
antigen-coated microplate wells |
soluble egg-protein, purifiied from Schistosoma mansoni eggs"soluble egg antigen" |
semi-quantitative | IgG |
96 x 01 |
EI 2300-9601 G |
| ELISA | Anti-Schistosoma ELISA (IgM) |
antigen-coated microplate wells |
purified antigen from adult Schistosoma mansoni "adult worm antigen" |
semi-quantitative | IgM |
96 x 01 |
EI 2300-9601 M |
| IIFT |
Leishmania donovani (promastigote) |
protozoan smear |
Leishmania donovani |
IgG IgM IgG IgM |
10 x 05 10 x 05 10 x 10 10 x 10 |
FI 2231-1005 G FI 2231-1005 M FI 2231-1010 G FI 2231-1010 M |
|
| ELISA | Anti-Trypanosoma cruzi ELISA (IgG) |
antigen-coated microplate wells |
recombinant fusion protein of antigen epitopes from Trypanosoma cruzi |
2/20/200 RU/ml | IgG |
96 x 01 |
EI 2212-9601 G |
| ELISA | Anti-Leishmania ELISA (IgG) |
antigen-coated microplate wells |
antigen combination of specific recombinant L. donovani antigens and purified native antigens from L. infantum |
200-50-20-2 RU/ml | IgG |
96 x 01 |
EI 2232-9601 G |
| ELISA | Anti-Plasmodium ELISA (IgG) |
antigen-coated microplate wells |
optimized mixture of rec. antigens from 5 human pathogeneous species |
semi-quantitative | IgG |
96 x 01 |
EI 2260-9601 G |
| ELISA | Anti-Toxocara ELISA (IgG) |
antigen-coated microplate wells |
semi-quantitative | IgG |
96 x 01 |
EI 2311-9601 G | |
| ELISA | Anti-Echinococcus ELISA (IgG) |
antigen-coated microplate wells |
native Echinococcus multilocularis antigen EmVF |
semi-quantitative | IgG |
96 x 01 |
EI 2320-9601-1 G |
| ELISA | Anti-Trichinella ELISA (IgG) |
antigen-coated microplate wells |
antigens from Trichinella muscle larvae |
semi-quantitative | IgG |
96 x 01 |
EI 2360-9601 G |
| WESTERNBLOT |
antibodies against Echinococcus IgG positive control |
IgG |
50 x 05 |
CW 2321-5005 G | |||
| WESTERNBLOT | Anti-Toxocara Westernblot (IgG) | Westernblot | Toxocara whole lysate | IgG |
16 x 01 |
DY 2311-1601 G | |
| WESTERNBLOT |
EUROLINE-WB Anti-Echinococcus (IgG) Echinococcus multilocularis and Echinococcus granulosus |
Westernblot |
Echinococcus multilocularis and Echinococcus granulosus |
IgG IgG |
16 x 01 48 x 01 |
DY 2321-1601-2 G DY 2321-4801-2 G |
|
| IIFT |
Toxoplasma gondii |
protozoan smear |
Toxoplasma gondii |
IgG IgM IgG IgM |
10 x 05 10 x 05 10 x 10 10 x 10 |
FI 2410-1005 G FI 2410-1005 M FI 2410-1010 G FI 2410-1010 M |
|
| ELISA | Anti-Toxoplasma gondii ELISA (IgA) |
antigen-coated microplate wells |
native antigens of Toxoplasma gondii |
semi-quantitative | IgA |
96 x 01 |
EI 2410-9601 A |
| ELISA | Anti-Toxoplasma gondii ELISA (IgM) |
antigen-coated microplate wells |
native antigens of Toxoplasma gondii |
semi-quantitative | IgM |
96 x 01 |
EI 2410-9601 M |
| ELISA |
Avidity: Anti-Toxoplasma gondii ELISA (IgG) avidity determination |
antigen-coated microplate wells |
native antigens of Toxoplasma gondii |
1/10/200 IU/ml | IgG |
96 x 01 |
EI 2410-9601-1 G |
| ELISA | Anti-Toxoplasma gondii ELISA 2.0 (IgG) |
antigen-coated microplate wells |
native antigens of Toxoplasma gondii |
IgG |
96 x 01 |
EI 2410-9601-2 G | |
| ChLIA | IDS TOXO IgG | antigenic coated magnetic particles | Toxoplasma gondii antigens |
quantitative |
100 x 01 |
IS-ID50011 | |
| ChLIA | IDS TOXO IgM | Anti-IgM-coated magnetic particles | Conjugate: Toxoplasma gondii antigens |
quantitative |
100 x 01 |
IS-ID50021 | |
| ChLIA | IDS TOXO Control Set | 3 x 1.5 ml Control 1/2 | human serum |
2 concentrations |
IS-ID50301 | ||
| ChLIA | IDS TOXO IgG Avidity | antigenic coated magnetic particles | Toxoplasma gondii antigens |
semi-quantitative |
50 x 01 |
IS-ID51011 | |
| ChLIA | IDS TOXO Avidity Control Set | 3 x 1.0 ml Control 1/2 | human serum |
2 concentrations |
IS-ID51301 | ||
| PCR | EURORealTime Toxoplasma gondii |
01 x 100 01 x 25 |
MP 2410-0100 MP 2410-0125 |
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* For research use only, not for in vitro diagnostic use in the sense of EU directive 98/79/EC. 1 Product manufactured by third party. Please contact your local Euroimmun representative for more information. | |||||||