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Gastrointestinal infections

Clinical information

Gastrointestinal infections can be caused by bacteria, viruses and parasites and are among the most frequent infectious diseases. They manifest as gastritis, diarrhoea, vomiting or unspecific symptoms which occur within just a few hours after uptake of the pathogen in the case of some bacterial or viral infections and may, in rare cases, lead to chronic sequelae. Infections with parasitic pathogens, however, usually take a chronic course.

Diagnostics

Gastrointestinal infections are usually self-limiting, especially those caused by viruses. In most cases it is therefore sufficient to treat the symptoms. Direct pathogen detection may be useful in outbreaks and in risk patients. Bacteria such as Yersinia and Campylobacter may cause immunologically mediated secondary diseases, e. g. reactive arthritis. Here, serological tests may support the diagnosis. Infections with Helicobacter pylori may cause chronic active gastritis and complications such as gastroduodenal ulcer disease, stomach carcinoma or lymphoma. Antibody detection is recommended in suspected cases of non-acute or chronic infection. Parasitic pathogens such as Schistosoma and Strongyloides stercoralis can also cause gastrointestinal symptoms with chronic courses. Direct and indirect methods are applied for diagnostics. In general, specific antibody detection is suitable to support the diagnosis in suspected cases of chronic courses or secondary diseases, but not for diagnostics in acute cases.

Methods
Technology Parameter Substrate Species Calibration Ig Class Format Order No.
ELISA Anti-Hepatitis E Virus (HEV) ELISA (IgG) antigen-coated
microplate wells
recombinant target antigens
from Hepatitis E virus genotypes
1 and 3
0,2/1/10/25 IU/ml IgG 96 x 01
EI 2525-9601 G
ELISA Anti-Hepatitis E Virus (HEV) ELISA (IgM) antigen-coated
microplate wells
recombinant target antigens
from Hepatitis E virus genotypes
1 and 3
semi-quantitative IgM 96 x 01
EI 2525-9601 M
EUROLINE Positive control serum (IgA, 50x concentrated)
for Hepatitis E Virus
IgA 05 x 07
CL 2525-0507 A
EUROLINE Positive control serum (IgG, 50x concentrated)
for hepatitis E virus
IgG 05 x 07
CL 2525-0507 G
EUROLINE EUROLINE Anti-Hepatitis E Virus (IgA)
(separat: GT1 ORF2, GT2 ORF2,
GT3 ORF2, GT4 ORF2)
EUROLINE IgA
IgA
IgA
05 x 10
16 x 01
64 x 01
DN 2525-0510 A
DN 2525-1601 A
DN 2525-6401 A
EUROLINE EUROLINE Anti-Hepatitis E Virus (IgG)
(separat: GT1 ORF2, GT2 ORF2,
GT3 ORF2, GT4 ORF2)
EUROLINE IgG
IgG
16 x 01
64 x 01
DN 2525-1601 G
DN 2525-6401 G
IIFT Listeria
monocytogenes
1/2a and 4b
bacterial
smears
(2 BIOCHIPs per field)
Listeria
monocytogenes
1/2a and 4b
IgG
IgG
10 x 05
10 x 10
FI 2141-1005-1 G
FI 2141-1010-1 G
ELISA Anti-Helicobacter pylori ELISA (IgA) antigen-coated
microplate wells
detergent extract
from Helicobacter pylori
semi-quantitative IgA 96 x 01
EI 2080-9601 A
ELISA Anti-Helicobacter pylori ELISA (IgG) antigen-coated
microplate wells
detergent extract
from Helicobacter pylori
2/20/200 RU/ml IgG 96 x 01
EI 2080-9601 G
ELISA Anti-Helicobacter pylori CagA ELISA (IgA) antigen-coated
microplate wells
recombinant CagA,
expression in E. coli
semi-quantitative IgA 96 x 01
EI 2081-9601 A
ELISA Anti-Campylobacter jejuni ELISA (IgA) antigen-coated
microplate wells
detergent extract
from Campylobacter jejuni
semi-quantitative IgA 96 x 01
EI 2091-9601 A
ELISA Anti-Campylobacter jejuni ELISA (IgG) antigen-coated
microplate wells
detergent extract
from Campylobacter jejuni
2/20/200 RU/ml IgG 96 x 01
EI 2091-9601 G
ELISA Anti-Yersinia enterocolitica ELISA (IgA) antigen-coated
microplate wells
recombinant Yop D
of Yersinia enterocolitica
semi-quantitative IgA 96 x 01
EI 2173-9601 A
ELISA Anti-Yersinia enterocolitica ELISA (IgG) antigen-coated
microplate wells
native isolated virulence factors
(release proteins, Yop)
of Yersinia enterocolitica
2/20/200 RU/ml IgG 96 x 01
EI 2173-9601 G
EUROLINE positive control serum: IgA, human, 50x concentrated
for Yersinia enterocolitica IgA EUROLINE
IgA 05 x 07
CL 2173-0507 A
EUROLINE positive control serum: IgG, human, 50x concentrated
for Yersinia enterocolitica IgG EUROLINE
IgG 05 x 07
CL 2173-0507 G
EUROLINE EUROLINE Anti-Yersinia enterocolitica (IgA)
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
EUROLINE IgA
IgA
16 x 01
64 x 01
DN 2173-1601 A
DN 2173-6401 A
EUROLINE EUROLINE Anti-Yersinia enterocolitica (IgG)
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
EUROLINE IgG
IgG
16 x 01
64 x 01
DN 2173-1601 G
DN 2173-6401 G
WESTERNBLOT antibodies against Helicobacter pylori
IgA positive control
IgA 50 x 05
CW 2080-5005 A
WESTERNBLOT antibodies against Helicobacter pylori
IgG positive control
IgG 50 x 05
CW 2080-5005 G
WESTERNBLOT antibodies against Yersinia enterocolitica
IgA positive control
(for diagnosing various forms of arthritis)
IgA 50 x 05
CW 2173-5005 A
WESTERNBLOT antibodies against Yersinia enterocolitica
IgG positive control
(for diagnosing various forms of arthritis)
IgG 50 x 05
CW 2173-5005 G
WESTERNBLOT Anti-Helicobacter pylori EUROLINE-Westernblot (IgA) Westernblot whole antigen of H. pylori,
plus recombinant VacA and CagA antigen
IgA
IgA
16 x 01
30 x 01
DY 2080-1601-1 A
DY 2080-3001-1 A
WESTERNBLOT Anti-Helicobacter pylori EUROLINE-Westernblot (IgG) Westernblot whole antigen of H. pylori,
plus recombinant VacA and CagA antigen
IgG
IgG
16 x 01
30 x 01
DY 2080-1601-1 G
DY 2080-3001-1 G
WESTERNBLOT Anti-Yersinia enterocolitica WESTERNBLOT (IgA)
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
Westernblot isolated virulence factors
(release proteins, Yop)
of Yersinia enterocolitica
IgA
IgA
16 x 01
30 x 01
DY 2173-1601 A
DY 2173-3001 A
WESTERNBLOT Anti-Yersinia enterocolitica WESTERNBLOT (IgG)
Detection of antibodies against virulence factors of the
Yersinia enterocolitica pathogen in human serum
(for diagnosing various forms of arthritis).
Westernblot isolated virulence factors
(release proteins, Yop)
of Yersinia enterocolitica
IgG
IgG
16 x 01
30 x 01
DY 2173-1601 G
DY 2173-3001 G
IIFT Schistosoma
mansoni
frozen
sections
Schistosoma
mansoni, adult
IgG
IgM
10 x 05
10 x 05
FI 2300-1005 G
FI 2300-1005 M
ELISA Anti-Strongyloides ELISA (IgG) antigen-coated
microplate wells
native antigens from
Strongyloides larvae
semi-quantitative IgG 96 x 01
EI 2290-9601 G
ELISA Anti-Schistosoma ELISA (IgG) antigen-coated
microplate wells
soluble egg-protein, purifiied
from Schistosoma mansoni eggs"soluble egg antigen"
semi-quantitative IgG 96 x 01
EI 2300-9601 G
ELISA Anti-Schistosoma ELISA (IgM) antigen-coated
microplate wells
purified antigen from adult
Schistosoma mansoni "adult worm antigen"
semi-quantitative IgM 96 x 01
EI 2300-9601 M
ELISA Anti-Adenovirus ELISA (IgA) antigen-coated
microplate wells
native antigens
from Adenovirus
semi-quantitative IgA 96 x 01
EI 2680-9601 A
ELISA Anti-Adenovirus ELISA (IgG) antigen-coated
microplate wells
native antigens
from Adenovirus
2/20/200 RU/ml IgG 96 x 01
EI 2680-9601 G
ELISA Anti-Adenovirus ELISA (IgM) antigen-coated
microplate wells
native antigens
from Adenovirus
semi-quantitative IgM 96 x 01
EI 2680-9601 M
* For research use only, not for in vitro diagnostic use in the sense of EU directive 98/79/EC.
1 Product manufactured by third party. Please contact your local Euroimmun representative for more information.