Clinical information
Gastrointestinal infections can be caused by bacteria, viruses and parasites and are among the most frequent infectious diseases. They manifest as gastritis, diarrhoea, vomiting or unspecific symptoms which occur within just a few hours after uptake of the pathogen in the case of some bacterial or viral infections and may, in rare cases, lead to chronic sequelae. Infections with parasitic pathogens, however, usually take a chronic course.
Diagnostics
Gastrointestinal infections are usually self-limiting, especially those caused by viruses. In most cases it is therefore sufficient to treat the symptoms. Direct pathogen detection may be useful in outbreaks and in risk patients. Bacteria such as Yersinia and Campylobacter may cause immunologically mediated secondary diseases, e. g. reactive arthritis. Here, serological tests may support the diagnosis. Infections with Helicobacter pylori may cause chronic active gastritis and complications such as gastroduodenal ulcer disease, stomach carcinoma or lymphoma. Antibody detection is recommended in suspected cases of non-acute or chronic infection. Parasitic pathogens such as Schistosoma and Strongyloides stercoralis can also cause gastrointestinal symptoms with chronic courses. Direct and indirect methods are applied for diagnostics. In general, specific antibody detection is suitable to support the diagnosis in suspected cases of chronic courses or secondary diseases, but not for diagnostics in acute cases.
| Technology | Parameter | Substrate | Species | Calibration | Ig Class | Format | Order No. |
|---|---|---|---|---|---|---|---|
| ELISA | Anti-Hepatitis E Virus (HEV) ELISA (IgG) |
antigen-coated microplate wells |
recombinant target antigens from Hepatitis E virus genotypes 1 and 3 |
0,2/1/10/25 IU/ml | IgG |
96 x 01 |
EI 2525-9601 G |
| ELISA | Anti-Hepatitis E Virus (HEV) ELISA (IgM) |
antigen-coated microplate wells |
recombinant target antigens from Hepatitis E virus genotypes 1 and 3 |
semi-quantitative | IgM |
96 x 01 |
EI 2525-9601 M |
| EUROLINE |
Positive control serum (IgA, 50x concentrated) for Hepatitis E Virus |
IgA |
05 x 07 |
CL 2525-0507 A | |||
| EUROLINE |
Positive control serum (IgG, 50x concentrated) for hepatitis E virus |
IgG |
05 x 07 |
CL 2525-0507 G | |||
| EUROLINE |
EUROLINE Anti-Hepatitis E Virus (IgA) (separat: GT1 ORF2, GT2 ORF2, GT3 ORF2, GT4 ORF2) |
EUROLINE | IgA IgA IgA |
05 x 10 16 x 01 64 x 01 |
DN 2525-0510 A DN 2525-1601 A DN 2525-6401 A |
||
| EUROLINE |
EUROLINE Anti-Hepatitis E Virus (IgG) (separat: GT1 ORF2, GT2 ORF2, GT3 ORF2, GT4 ORF2) |
EUROLINE | IgG IgG |
16 x 01 64 x 01 |
DN 2525-1601 G DN 2525-6401 G |
||
| IIFT |
Listeria monocytogenes 1/2a and 4b |
bacterial smears (2 BIOCHIPs per field) |
Listeria monocytogenes 1/2a and 4b |
IgG IgG |
10 x 05 10 x 10 |
FI 2141-1005-1 G FI 2141-1010-1 G |
|
| ELISA | Anti-Helicobacter pylori ELISA (IgA) |
antigen-coated microplate wells |
detergent extract from Helicobacter pylori |
semi-quantitative | IgA |
96 x 01 |
EI 2080-9601 A |
| ELISA | Anti-Helicobacter pylori ELISA (IgG) |
antigen-coated microplate wells |
detergent extract from Helicobacter pylori |
2/20/200 RU/ml | IgG |
96 x 01 |
EI 2080-9601 G |
| ELISA | Anti-Helicobacter pylori CagA ELISA (IgA) |
antigen-coated microplate wells |
recombinant CagA, expression in E. coli |
semi-quantitative | IgA |
96 x 01 |
EI 2081-9601 A |
| ELISA | Anti-Campylobacter jejuni ELISA (IgA) |
antigen-coated microplate wells |
detergent extract from Campylobacter jejuni |
semi-quantitative | IgA |
96 x 01 |
EI 2091-9601 A |
| ELISA | Anti-Campylobacter jejuni ELISA (IgG) |
antigen-coated microplate wells |
detergent extract from Campylobacter jejuni |
2/20/200 RU/ml | IgG |
96 x 01 |
EI 2091-9601 G |
| ELISA | Anti-Yersinia enterocolitica ELISA (IgA) |
antigen-coated microplate wells |
recombinant Yop D of Yersinia enterocolitica |
semi-quantitative | IgA |
96 x 01 |
EI 2173-9601 A |
| ELISA | Anti-Yersinia enterocolitica ELISA (IgG) |
antigen-coated microplate wells |
native isolated virulence factors (release proteins, Yop) of Yersinia enterocolitica |
2/20/200 RU/ml | IgG |
96 x 01 |
EI 2173-9601 G |
| EUROLINE |
positive control serum: IgA, human, 50x concentrated for Yersinia enterocolitica IgA EUROLINE |
IgA |
05 x 07 |
CL 2173-0507 A | |||
| EUROLINE |
positive control serum: IgG, human, 50x concentrated for Yersinia enterocolitica IgG EUROLINE |
IgG |
05 x 07 |
CL 2173-0507 G | |||
| EUROLINE |
EUROLINE Anti-Yersinia enterocolitica (IgA) Detection of antibodies against virulence factors of the Yersinia enterocolitica pathogen in human serum (for diagnosing various forms of arthritis). |
EUROLINE | IgA IgA |
16 x 01 64 x 01 |
DN 2173-1601 A DN 2173-6401 A |
||
| EUROLINE |
EUROLINE Anti-Yersinia enterocolitica (IgG) Detection of antibodies against virulence factors of the Yersinia enterocolitica pathogen in human serum (for diagnosing various forms of arthritis). |
EUROLINE | IgG IgG |
16 x 01 64 x 01 |
DN 2173-1601 G DN 2173-6401 G |
||
| WESTERNBLOT |
antibodies against Helicobacter pylori IgA positive control |
IgA |
50 x 05 |
CW 2080-5005 A | |||
| WESTERNBLOT |
antibodies against Helicobacter pylori IgG positive control |
IgG |
50 x 05 |
CW 2080-5005 G | |||
| WESTERNBLOT |
antibodies against Yersinia enterocolitica IgA positive control (for diagnosing various forms of arthritis) |
IgA |
50 x 05 |
CW 2173-5005 A | |||
| WESTERNBLOT |
antibodies against Yersinia enterocolitica IgG positive control (for diagnosing various forms of arthritis) |
IgG |
50 x 05 |
CW 2173-5005 G | |||
| WESTERNBLOT | Anti-Helicobacter pylori EUROLINE-Westernblot (IgA) | Westernblot |
whole antigen of H. pylori, plus recombinant VacA and CagA antigen |
IgA IgA |
16 x 01 30 x 01 |
DY 2080-1601-1 A DY 2080-3001-1 A |
|
| WESTERNBLOT | Anti-Helicobacter pylori EUROLINE-Westernblot (IgG) | Westernblot |
whole antigen of H. pylori, plus recombinant VacA and CagA antigen |
IgG IgG |
16 x 01 30 x 01 |
DY 2080-1601-1 G DY 2080-3001-1 G |
|
| WESTERNBLOT |
Anti-Yersinia enterocolitica WESTERNBLOT (IgA) Detection of antibodies against virulence factors of the Yersinia enterocolitica pathogen in human serum (for diagnosing various forms of arthritis). |
Westernblot |
isolated virulence factors (release proteins, Yop) of Yersinia enterocolitica |
IgA IgA |
16 x 01 30 x 01 |
DY 2173-1601 A DY 2173-3001 A |
|
| WESTERNBLOT |
Anti-Yersinia enterocolitica WESTERNBLOT (IgG) Detection of antibodies against virulence factors of the Yersinia enterocolitica pathogen in human serum (for diagnosing various forms of arthritis). |
Westernblot |
isolated virulence factors (release proteins, Yop) of Yersinia enterocolitica |
IgG IgG |
16 x 01 30 x 01 |
DY 2173-1601 G DY 2173-3001 G |
|
| IIFT |
Schistosoma mansoni |
frozen sections |
Schistosoma mansoni, adult |
IgG IgM |
10 x 05 10 x 05 |
FI 2300-1005 G FI 2300-1005 M |
|
| ELISA | Anti-Strongyloides ELISA (IgG) |
antigen-coated microplate wells |
native antigens from Strongyloides larvae |
semi-quantitative | IgG |
96 x 01 |
EI 2290-9601 G |
| ELISA | Anti-Schistosoma ELISA (IgG) |
antigen-coated microplate wells |
soluble egg-protein, purifiied from Schistosoma mansoni eggs"soluble egg antigen" |
semi-quantitative | IgG |
96 x 01 |
EI 2300-9601 G |
| ELISA | Anti-Schistosoma ELISA (IgM) |
antigen-coated microplate wells |
purified antigen from adult Schistosoma mansoni "adult worm antigen" |
semi-quantitative | IgM |
96 x 01 |
EI 2300-9601 M |
| ELISA | Anti-Adenovirus ELISA (IgA) |
antigen-coated microplate wells |
native antigens from Adenovirus |
semi-quantitative | IgA |
96 x 01 |
EI 2680-9601 A |
| ELISA | Anti-Adenovirus ELISA (IgG) |
antigen-coated microplate wells |
native antigens from Adenovirus |
2/20/200 RU/ml | IgG |
96 x 01 |
EI 2680-9601 G |
| ELISA | Anti-Adenovirus ELISA (IgM) |
antigen-coated microplate wells |
native antigens from Adenovirus |
semi-quantitative | IgM |
96 x 01 |
EI 2680-9601 M |
|
* For research use only, not for in vitro diagnostic use in the sense of EU directive 98/79/EC. 1 Product manufactured by third party. Please contact your local Euroimmun representative for more information. | |||||||