Vitamin D

Active vitamin D hormone (1,25-dihydroxy vitamin D) regulates the uptake of calcium from the intestinal tract, the mineralisation of the bones, the differentiation of osteoblasts and bone matrix synthesis. Even a slight vitamin D deficiency in the blood causes an increase in bone atrophy. Moreover, hypovitaminosis D is a risk factor for autoimmune diseases (e.g. multiple sclerosis, Crohn's disease, type 1 diabetes mellitus), infectious diseases (e.g. infections of the respiratory tract, tuberculosis) and cardiovascular diseases.

The 25-OH Vitamin D ELISA is designed for serological determination of vitamin D concentrations in humans. The serum level of 25-OH vitamin D, which of all vitamin D metabolites in the blood stores most vitamin D, is a suitable indicator of the actual vitamin D supply in the human body.

The quantitative determination of 25-OH vitamin D in serum with the 25-OH Vitamin D ELISA can be fully automated.