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Dr. Oliver Sendscheid

Dr. Oliver Sendscheid
+49 451 5855-25454
o.sendscheid-delete-@euroimmun.de

Autoantibodies against phospholipase A2 receptor

Anti-phospholipase A2 receptor

Transfected cells: antibodies against PLA2R.
  • Detection of antibodies against
    phospholipase A2 receptor (PLA2R).
  • Indication: primary membranous nephropathy (MN), also membranous glomerulonephritis (MGN).
  • Initial dilution 1 : 10; conjugate class anti-human IgG, FITC-labelled.
  • The Anti-Phospholipase A2 Receptor IIFT utilises transfected cells as standard substrate. Antibodies against PLA2R react with the transfected cells of the test substrate and produce a cytoplasmic fluorescence, in part with fluorescence of the cell membrane.
  • The detection of antibodies against phospholipase A2 receptors is highly specific and aids differential diagnosis of primary MN from the secondary form.

ProductOrder number
Anti-Phospholipase A2 Receptor IIFT  FA 1254-50

Anti-phospholipase A2 receptor

Incubated Anti-PLA2R ELISA.
  • Monospecific detection of antibodies against phospholipase A2 receptor (PLA2R).
  • Indication: primary membranous nephropathy (MN), also  membranous glomerulonephritis (MGN).
  • Serum dilution 1 : 101, conjugate class anti-human IgG, POD-labelled.
  • 5-point calibration, quantitative.
  • Antigen: recombinant, human cDNA expressed in a human cell line.
  • Anti-PLA2R antibody titers serve as a marker for deciding on the necessity and extent of immunosuppressive therapy required. They are also useful for monitoring the disease course of patients undergoing therapy.

ProductOrder number
Anti-Phospholipase A2 Receptor ELISA  EA 1254 G