- Transfected cells: antibodies against PLA2R.
- Detection of antibodies against phospholipase A2 receptor (PLA2R).
- Indication: primary membranous glomerulonephritis (MGN, also idiopathic membranous nephropathy IMN).
- Initial dilution 1 : 10; conjugate class anti-human IgG, FITC labelled.
- The Anti-Phospholipase A2 receptor IIFT uses transfected cells as the standard substrate. Antibodies against PLA2R react with the transfected cells of the test substrate. They induce a cytoplasmic fluorescence, with some fluorescence of the cell membrane.
- The detection of antibodies against phospholipase A2 receptors (PLA2R) is very specific and helps to differentiate primary membranous nephropathy from the secondary form of the disease.
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- Incubated ELISA Anti-PLA2R.
- Monospecific detection of antibodies against phospholipase A2 receptor (PLA2R).
- Indication: primary membranous glomerulonephritis (MGN, also idiopathic membranous nephropathy IMN).
- Serum dilution 1: 100, conjugate class anti-human IgG, POD-labelled.
- 5-point calibration, quantitative.
- Antigen: recombinant, human c-DNA expressed in human cell line.
- The anti-PLA2R antibody titer is a marker that indicates whether immunosuppressive therapy is required and which type should be used. It is also useful for monitoring the patient during therapy.
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